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Association of Limited Health Literacy with Clinical and Patient-Reported...
Background/Purpose: Health literacy (HL) is an important social determinant of health defined as the ability to understand and use health information. Limited HL is associated with worse clinical...
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A Prediction Model to Distinguish Patients with Multisystem Inflammatory...
Background/Purpose: Multisystem inflammatory syndrome in children (MIS-C) is a rare consequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MIS-C shares features with common...
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A Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study of Safety,...
Background/Purpose: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a prevalent and morbid condition leading to premature death in 10% of those affected. The TRAIL1 trial was a...
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Cardiovascular Risk of Hydroxychloroquine in the Treatment of Rheumatoid...
Background/Purpose: Hydroxychloroquine (HCQ) is a commonly used 1st-line disease-modifying antirheumatic drug (DMARD) for patients with rheumatoid arthritis (RA) in the U.S., while methotrexate (MTX)...
View ArticleCOVID-19 Vaccine in Immunosuppressed Adults with Autoimmune Diseases
Background/Purpose: Immunocompromised conditions and/or a history of autoimmune disease were exclusion criteria of the initial SARS-CoV-2 vaccines clinical trials. We assessed the safety and...
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Humoral and Cellular Immune Responses to a Second Dose of COVID-19 Vaccine...
Background/Purpose: COVID-19 vaccines have robust immunogenicity in the general population. Data on individuals with immune-mediated inflammatory diseases who are taking immunosuppressants remains...
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COVID-19 Vaccine Antibody Responses in Patients Treated with B-Cell Agents...
Background/Purpose: Optimal COVID-19 vaccine responses are necessary to protect against severe infection. Patients with systemic rheumatic diseases (SRD) are at risk for not mounting adequate immune...
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Secukinumab in Giant Cell Arteritis: A Randomized, Parallel-group,...
Background/Purpose: Little is known about glucocorticoid-sparing agents in giant cell arteritis (GCA) except for IL-6 inhibition. Secukinumab (SEC) has shown significant improvements in the signs and...
View ArticleClik here to view.
Association of Limited Health Literacy with Clinical and Patient-Reported...
Background/Purpose: Health literacy (HL) is an important social determinant of health defined as the ability to understand and use health information. Limited HL is associated with worse clinical...
View ArticleClik here to view.
A Prediction Model to Distinguish Patients with Multisystem Inflammatory...
Background/Purpose: Multisystem inflammatory syndrome in children (MIS-C) is a rare consequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MIS-C shares features with common...
View ArticleClik here to view.
A Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study of Safety,...
Background/Purpose: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a prevalent and morbid condition leading to premature death in 10% of those affected. The TRAIL1 trial was a...
View ArticleClik here to view.
Cardiovascular Risk of Hydroxychloroquine in the Treatment of Rheumatoid...
Background/Purpose: Hydroxychloroquine (HCQ) is a commonly used 1st-line disease-modifying antirheumatic drug (DMARD) for patients with rheumatoid arthritis (RA) in the U.S., while methotrexate (MTX)...
View ArticleClik here to view.
Neither Add-on nor Withdrawal of Methotrexate Impacts Efficacy of IL12/23...
Background/Purpose: Methotrexate (MTX) is often used as first-line DMARD-therapy in active psoriatic arthritis (PsA). Randomized clinical trials usually require treatment failure or intolerance of...
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Efficacy and Safety of Subcutaneous Belimumab (BEL) and Rituximab (RTX)...
Background/Purpose: Disease control remains an unmet need in SLE. The rationale for sequential BEL and RTX therapy in SLE was previously published.1 This study evaluated the efficacy, safety, and...
View ArticleCOVID-19 Vaccine in Immunosuppressed Adults with Autoimmune Diseases
Background/Purpose: Immunocompromised conditions and/or a history of autoimmune disease were exclusion criteria of the initial SARS-CoV-2 vaccines clinical trials. We assessed the safety and...
View ArticleClik here to view.
Humoral and Cellular Immune Responses to a Second Dose of COVID-19 Vaccine...
Background/Purpose: COVID-19 vaccines have robust immunogenicity in the general population. Data on individuals with immune-mediated inflammatory diseases who are taking immunosuppressants remains...
View ArticleClik here to view.
COVID-19 Vaccine Antibody Responses in Patients Treated with B-Cell Agents...
Background/Purpose: Optimal COVID-19 vaccine responses are necessary to protect against severe infection. Patients with systemic rheumatic diseases (SRD) are at risk for not mounting adequate immune...
View ArticleClik here to view.
Secukinumab in Giant Cell Arteritis: A Randomized, Parallel-group,...
Background/Purpose: Little is known about glucocorticoid-sparing agents in giant cell arteritis (GCA) except for IL-6 inhibition. Secukinumab (SEC) has shown significant improvements in the signs and...
View ArticleClik here to view.
SARS-CoV-2 Infections Among Vaccinated Individuals with Rheumatic Disease:...
Background/Purpose: While COVID-19 vaccinations are a critical tool to prevent severe infections, poor immunogenicity in immunocompromised people threatens vaccine effectiveness. We analyzed clinical...
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Efficacy of Emapalumab, an Anti-IFNγ Antibody in Patients with Macrophage...
Background/Purpose: MAS is a life-threatening complication of rheumatic diseases, occurring most frequently in sJIA. The mainstay of MAS treatment is high dose GCs; however, GCs do not always provide...
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